Written in English
|Statement||by William C. Stanley.|
|The Physical Object|
|Pagination||vii, 191 leaves|
|Number of Pages||191|
To investigate the relationships between oxygen consumption (VO2) and the rates of systemic lactate appearance (Ra) and disappearance (Rd), six healthy males were studied at rest and during continuous graded exercise using a primed continuous infusion of lactate tracer. Subjects exercised for 6 min at , , , and 1, kg. m. minCited by: In the heart, oxidative energy production from lactate is higher than from glucose both at rest and during moderate intensity exercise (28). In addition, the liver and kidney are also involved in. Systemic lactate kinetics during graded exercise in man. Stanley WC, Gertz EW, Wisneski JA, Morris DL, Neese RA, Brooks GA. To investigate the relationships between oxygen consumption (VO2) and the rates of systemic lactate appearance (Ra) and disappearance (Rd), six healthy males were studied at rest and during continuous graded exercise using Cited by: It was found that during 30 min of exercise % of the administered [14 C]lactate was recovered as 14 CO 2 in the expired gas, whereas at rest only % was recovered in the same period. 4. After injection of [ 14 C]lactate the blood 14 C concentration and the specific activity of the blood lactate declined very rapidly.
Whole body and limb lactate kinetics: At rest, the arterial lactate concentration and rate of appearance of lactate (R a) were higher in patients vs. healthy exercise, the arterial lactate concentration increased 3-fold in the patients, but remained unchanged in healthy controls (Fig. 1A).R a increased almost 3-fold during exercise in the patients, but only increased (p. Comparison of parameters of leg and whole body lactate metabolism in men during rest and exercise, before and after training. Rest Pretraining Rest Posttraining 45% Pretraining 65% Pretraining ABT Posttraining RLT Posttraining %Lactate R d oxidized: ± ± ± ± ± Abstract. Results of kinetic tracer studies on several mammalian species during rest and prolonged sustained exercise indicate that lactate is a metabolic intermediate which is very active in supplying carbon for a number of important physiological processes. Therefore, we investigate if blood lactate concentration could interfere with substrate utilization during exercise (a situation of increased lactate production) in type 2 diabetic patients. Furthermore, we have investigated lactate transport capacity and quantified MCT1 in RBCs. 2. Materials and methods Population.
Corresponding effects on lactate kinetics as a central aspect of anaerobic capacity were not observed in the present study, but a positive influence of HIIT on ANC, especially for HIIT formats with high/maximum stimulation and a load duration of between 20 seconds and 5 minutes/interval, was ascertained [3, 9, 14, 15]. Based on a literature review, the current study aimed to construct mathematical models of lactate production and removal in both muscles and blood during steady state and at varying intensities during whole-body exercise. In order to experimentally test the models in dynamic situations, a cross-country skier performed laboratory tests while treadmill roller skiing, from where work rate. Figure 2 shows the course of La and pH at rest, during exercise and findings are also in agreement with a study that investigated lactate (La] kinetics in boys and men following all-out. Plasma lactate concentrations and their trends over time are used for clinical prognosis, and to guide treatment, in critically ill patients. Although heavily relied upon for clinical decision-making, lactate kinetics of these patients is sparsely studied. To establish and validate a feasible method to study lactate kinetics in critically ill patients. Healthy volunteers (n = 6) received.